The Best of Our Knowledge explores topics on learning, education and research.On this episode, we’ll learn how artificial intelligence is allowing scientists to understand brain function. A new algorithm illuminates the brain’s internal wiring. Researchers are gaining new insight into the brain’s reward system.

We're joined by Dr. Michael Ormont, Director of Wound Care and Hyperbaric Medicine at Vassar Brothers Medical Center in Poughkeepsie, NY, and Northern Dutchess Hospital in Rhinebeck, NY. Ray Graf hosts.

Over the last 40 years few comedians have been a part of so many iconic beloved projects than Larry Charles. Larry was one of the original writers and producers of the first five seasons of “Seinfeld,” he executive produced both “Curb Your Enthusiasm” and “Entourage” while directing 18 episodes of “Curb,” and served as the showrunner for “Mad About You.” His film directing credits include “Borat,” “Bruno,” and “The Dictator,” as well as the documentary “Religulous” with Bill Marr, and “Masked and Anonymous” with Bob Dylan.Larry Charles writes about these 40 years of blood, guts, and laughter in his new memoir “Comedy Samurai: Forty Years of Blood, Guts, and Laughter.”

The latest nation's report card shows that American children’s reading skills reached new lows, while there is a debate about the best way to teach reading in school. Maya Payne Smart is a writer, parent educator, and literacy advocate argues that America’s reading crisis begins well before children enter kindergarten. She says it starts at birth, which is why she wrote a step-by-step guide for parents to do what it takes to set their children up to thrive as readers from day one to early elementary school. The name of the book is “Reading for Our Lives: The Urgency of Early Literacy and the Action Plan to Help Your Child.”