The best of The Best of Our Knowledge: 2025

By Lucas Willard,

Madeleine Reynolds

Published December 29, 2025 at 3:00 PM EST

Rendering of a layer 5 Martinotti cell (grey) reconstructed from a large-scale electron microscopy dataset. The output synapses (bright spots) are color-coded by the target cell type. Red dots are synapses made onto excitatory layer 2/3 pyramidal cells and cyan dots are onto intra-telencephalic-projecting excitatory neurons in layer 5.

The Best of Our Knowledge explores topics on learning, education, and research.

This week we’ll celebrate the best of The Best of Our Knowledge in 2025.

We’ll learn about a new color that humans normally can’t see, a project that created one of the most advanced maps of the brain, and research that uncovers truths to the extinction of the dinosaurs.

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